Stress-associated immune modulation : Relevance to viral infections and chronic fatigue syndrome
Identifieur interne : 003039 ( Main/Exploration ); précédent : 003038; suivant : 003040Stress-associated immune modulation : Relevance to viral infections and chronic fatigue syndrome
Auteurs : R. Glaser [États-Unis] ; J. K. Kiecolt-GlaserSource :
- The American journal of medicine [ 0002-9343 ] ; 1998.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Association, Homme.
English descriptors
- KwdEn :
Abstract
The frequent association of an active viral infection with the symptoms of CFS led researchers to hypothesize that chronic fatigue syndrome (CFS) is induced by a virus. Results of these studies indicated that despite clinical support for this hypothesis, there were no clear data linking viruses to CFS. In this overview, we will explore the interrelation of the immune, endocrine, and central nervous systems, and the possibility that stress and/or the reactivation/ replication of a latent virus (such as Epstein Barr virus) could modulate the immune system to induce CFS. Relevant research conducted in the developing field of psychoneuroimmunology will be reviewed, with a particular focus on cytokine synthesis, natural killer (NK) cell activity, and T-lymphocyte function, as they relate to CFS.
Affiliations:
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Le document en format XML
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Kiecolt-Glaser</name></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">99-0039814</idno><date when="1998">1998</date><idno type="stanalyst">PASCAL 99-0039814 INIST</idno><idno type="RBID">Pascal:99-0039814</idno><idno type="wicri:Area/PascalFrancis/Corpus">000314</idno><idno type="wicri:Area/PascalFrancis/Curation">000297</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">000234</idno><idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">000234</idno><idno type="wicri:doubleKey">0002-9343:1998:Glaser R:stress:associated:immune</idno><idno type="wicri:Area/Main/Merge">003050</idno><idno type="wicri:Area/Main/Curation">003039</idno><idno type="wicri:Area/Main/Exploration">003039</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Stress-associated immune modulation : Relevance to viral infections and chronic fatigue syndrome</title><author><name sortKey="Glaser, R" sort="Glaser, R" uniqKey="Glaser R" first="R." last="Glaser">R. Glaser</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Department of Medical Microbiology and Immunology and the Department of Psychiatry, Institute for Behavioral Medicine Research, Comprehensive Cancer Center, The Ohio State University College of Medicine</s1><s2>Columbus, Ohio</s2><s3>USA</s3></inist:fA14><country>États-Unis</country><placeName><region type="state">Ohio</region></placeName></affiliation></author><author><name sortKey="Kiecolt Glaser, J K" sort="Kiecolt Glaser, J K" uniqKey="Kiecolt Glaser J" first="J. K." last="Kiecolt-Glaser">J. K. Kiecolt-Glaser</name></author></analytic><series><title level="j" type="main">The American journal of medicine</title><title level="j" type="abbreviated">Am. j. med.</title><idno type="ISSN">0002-9343</idno><imprint><date when="1998">1998</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">The American journal of medicine</title><title level="j" type="abbreviated">Am. j. med.</title><idno type="ISSN">0002-9343</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Association</term><term>Chronic fatigue syndrome</term><term>Comparative study</term><term>Human</term><term>Immune response</term><term>Modulation</term><term>Prevalence</term><term>Risk factor</term><term>Stress</term><term>Viral disease</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Fatigue chronique syndrome</term><term>Prévalence</term><term>Association</term><term>Virose</term><term>Stress</term><term>Facteur risque</term><term>Réponse immune</term><term>Modulation</term><term>Etude comparative</term><term>Homme</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Association</term><term>Homme</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The frequent association of an active viral infection with the symptoms of CFS led researchers to hypothesize that chronic fatigue syndrome (CFS) is induced by a virus. Results of these studies indicated that despite clinical support for this hypothesis, there were no clear data linking viruses to CFS. In this overview, we will explore the interrelation of the immune, endocrine, and central nervous systems, and the possibility that stress and/or the reactivation/ replication of a latent virus (such as Epstein Barr virus) could modulate the immune system to induce CFS. Relevant research conducted in the developing field of psychoneuroimmunology will be reviewed, with a particular focus on cytokine synthesis, natural killer (NK) cell activity, and T-lymphocyte function, as they relate to CFS.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Ohio</li></region></list><tree><noCountry><name sortKey="Kiecolt Glaser, J K" sort="Kiecolt Glaser, J K" uniqKey="Kiecolt Glaser J" first="J. K." last="Kiecolt-Glaser">J. K. Kiecolt-Glaser</name></noCountry><country name="États-Unis"><region name="Ohio"><name sortKey="Glaser, R" sort="Glaser, R" uniqKey="Glaser R" first="R." last="Glaser">R. Glaser</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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